Macrolide resistance mediated by a Bifidobacterium breve membrane protein.

ABSTRACT: A gene coding for a hypothetical membrane protein from Bifidobacterium breve was expressed in Lactococcus lactis. Immunoblotting demonstrated that this protein is located in the membrane. Phenotypical changes in sensitivity towards 21 antibiotics were determined. The membrane protein-expressing cells showed higher levels of resistance to several macrolides.

SUBMITTER: Margolles A 

PROVIDER: S-EPMC1251533 | biostudies-literature | 2005 Oct

REPOSITORIES: biostudies-literature