Physical activity substitution: An overlooked constraint on energy expenditure during exercise and physical activity interventions.

ABSTRACT:

Aims

When exercise is prescribed, the new exercise could 'substitute' for pre-existing physical activity such that the net effect on energy expenditure is less than predicted. However, the impact of substitution has not been examined to date because of methodological spatiotemporal challenges. To overcome these challenges, we use mathematical modelling to examine the impact of substitution during prescribed exercise interventions.

Materials and methods

We modelled the impact of substitution during two prescribed exercise interventions (LOW and HIGH) on energy expenditure in 242 patients aged 63 ± 6 years recruited in the south-west of England. The increase in net daily energy expenditure after subtraction of pre-existing physical activity at the time of the new modelled pres

SUBMITTER: Thompson D 

PROVIDER: S-EPMC12515778 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature