Gender differences in the prescription of SGLT2 inhibitors in chronic kidney disease: A real-world database study.

ABSTRACT:

Aims

Chronic kidney disease (CKD) is a growing global health concern, and sodium-glucose cotransporter 2 (SGLT2) inhibitors have emerged as a key treatment strategy. While their kidney-protective effects are well established in both genders, women are prescribed these agents less frequently than men for the treatment of type 2 diabetes worldwide. However, data on gender differences in SGLT2 inhibitor prescriptions for CKD remain limited.

Materials and methods

This retrospective cohort study examined gender disparities in SGLT2 inhibitor prescriptions among individuals with CKD using a large-scale real-world database in Japan. Prescription claims data were extracted from health insurance claims records, and baseline clinical characteristics were obtained from health check-up

SUBMITTER: Azegami T 

PROVIDER: S-EPMC12515789 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature