Factors associated with acute clinically important postoperative nausea and vomiting in high-risk patients undergoing laparoscopic gastrointestinal surgery: a secondary analysis of the FDP-PONV trial.

ABSTRACT:

Background

Clinically important postoperative nausea and vomiting (CIPONV) is a highly distressing experience for patients after surgery. CIPONV can occur during the acute phase (0-24 h after surgery) or the delayed phase (25-120 h after surgery), with the acute phase being the primary concern. This study aimed to elucidate the key influencing factors associated with acute CIPONV. This study is based on data from the FDP-PONV trial, which exclusively enrolled patients with 3 or 4 Apfel risk factors. Thus, the findings are specific to this high-risk subgroup.

Methods

Patients participating in the FDP-PONV trial were all included in this study. Acute CIPONV was defined as the occurrence of postoperative nausea and vomiting (PONV) with a simplified PONV impact scale score of 5

SUBMITTER: Huang Y 

PROVIDER: S-EPMC12515918 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature