Effects of cognitive behavioral therapy on cognition, neuropsychiatric symptoms, and quality of life in Alzheimer's disease: a meta-analysis.

ABSTRACT:

Background

Alzheimer's disease (AD) is a progressive neurodegenerative disorder, often accompanied by cognitive decline and neuropsychiatric symptoms, which substantially impair patients' quality of life. Cognitive behavioral therapy (CBT) has shown effects in improving mood and quality of life in depression and anxiety, but systematic evidence of its application in AD is still limited.

Objective

This study aims to systematically assess the efficacy of CBT interventions on global cognition, neuropsychiatric symptoms (including depression severity) and Quality of Life (QoL) in AD.

Method

PubMed, Embase, Cochrane, and Web of Science databases were researched from the inception of each database to March 2025. The search strategy included MESH terms "Alzheimer Disease" an

SUBMITTER: Gao Y 

PROVIDER: S-EPMC12515942 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature