D3 lymph node dissection in colon cancer patients aged 90 years and over: Is it justified? A multi-institutional retrospective study.

ABSTRACT:

Aim

The oncological benefit of D3 lymph node dissection (D3 LND) for colon cancer in patients aged ≥90 years remains unclear. This study aimed to evaluate the impact of D3 LND on outcomes in this specific, vulnerable population.

Method

This retrospective cohort study evaluated 166 patients aged ≥90 years with pathological Stages II-III colon cancer undergoing non-D3 or D3 LND from a multicentre database (2011-2022). Postoperative complications, overall survival and cancer-specific survival were compared between LND groups using propensity score-weighted analyses.

Results

D3 LND group had significantly more females and laparoscopic procedures. Operation time was longer, and blood loss was lower in the D3 LND group. Postoperative complications and severe complications w

SUBMITTER: Teraishi F 

PROVIDER: S-EPMC12516024 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature