Ghost Ileostomy Versus Protective Ileostomy in Rectal Cancer Followed by Low Anterior Resection: A Randomized Feasibility Trial.

ABSTRACT:

Background

Anastomotic leakage remains a serious concern in rectal cancer patients undergoing neoadjuvant chemoradiotherapy (nCRT) followed by low anterior resection (LAR). To mitigate this risk, protective‌ ileostomy (PI) is often employed; ‌‌however, it carries its own complications and patient burden. This study aimed to evaluate the feasibility and clinical outcomes of ghost ileostomy (GI) as a potential alternative, aiming to reduce unnecessary stoma creation, related morbidity, readmission rates, and patient discomfort.

Methods

In this randomized, non-inferiority feasibility trial, patients with rectal cancer who had received nCRT and were scheduled for LAR were enrolled. Feasibility outcomes included recruitment rate, retention, intervention adherence, procedural fide

SUBMITTER: Meshkati Yazd SM 

PROVIDER: S-EPMC12516217 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature