Quantitative Shape Irregularity and Density Heterogeneity Predict Hematoma Expansion in Patients With Intracerebral Hemorrhage.

ABSTRACT:

Purpose

This study aimed to explore the association between quantitative shape irregularity and density heterogeneity of hematomas and hematoma expansion (HE) for intracerebral hemorrhage (ICH) patients.

Methods

This cohort study included patients arriving within 24 h of symptom onset between August 2021 and July 2022 as the derivation cohort and those between July 2023 and February 2024 as the external validation cohort. HE is defined as a hematoma increase of > 6 mL or > 33% from the baseline to the follow-up CT scan between 24 and 48 h. The least absolute shrinkage and selection operator (LASSO) regression was applied to select the traditional image signs to fit the logistic regression as Model 1. Afterwards, the surface regularity index (SRI) and density coefficient of v

SUBMITTER: Ji Z 

PROVIDER: S-EPMC12516230 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature