Associations of Stroke With Risk of Epilepsy: Results From the Atherosclerosis Risk in Communities (ARIC) Study.

ABSTRACT:

Objective

To estimate the risk of epilepsy associated with stroke in a community-based cohort, with consideration of stroke type, number, and severity.

Methods

Data from 15,100 Atherosclerosis Risk in Communities (ARIC) Study participants without stroke at baseline (1987-1989) were analyzed through 12/31/2022. Adjudicated stroke events were modeled as time-varying exposures. Epilepsy was defined using International Classification of Diseases Ninth/Tenth Revisions codes. Adjusted Fine and Gray proportional hazards models were used to estimate the risk of epilepsy associated with stroke.

Results

At baseline, the mean age of participants was 54 years, 55% were female, and 26% were of Black race. Over a median of 27 years, 1553 incident all-cause strokes occurred. The ris

SUBMITTER: Zhou J 

PROVIDER: S-EPMC12516231 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature