Culture-Negative Transcatheter Pulmonary Valve Endocarditis.

ABSTRACT:

Clinical condition

We present a case of transcatheter pulmonary valve endocarditis in a 38-year-old woman with a history of atrial septal defect, pulmonary stenosis, and bicuspid aortic valve, all previously repaired with mechanical and bioprosthetic valve replacements. Despite negative initial studies, ¹⁸F-fluorodeoxyglucose positron emission tomography-computed tomography revealed septic pulmonary emboli and abnormal uptake at the pulmonary valve. Metagenomic sequencing identified Haemophilus parainfluenzae as the pathogen.

Key questions

What is the differential diagnosis of a cardiac mass in this context? How should imaging and laboratory testing be approached in prosthetic valve endocarditis with negative studies? What surgical factors matter in patients with

SUBMITTER: Odukwe C 

PROVIDER: S-EPMC12516259 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature