PatchWorkPlot: simultaneous visualization of local alignments across multiple sequences.

ABSTRACT:

Motivation

Revealing structural variations within and across populations is crucial for understanding their diversification mechanisms and roles. Existing tools for visualization of structural variations often require labor-intensive figure preparation and are limited in their ability to integrate annotations.

Results

We developed PatchWorkPlot, a tool for automated visualization of pairwise alignments of multiple annotated sequences as dot plots combined into a single matrix. PatchWorkPlot enables exploration of positions, breakpoints, and architectures of structural variations across two or more sequences. The tool supports customization of visualization parameters and produces high-resolution, publication-ready figures. PatchWorkPlot significantly reduces manual work and

SUBMITTER: Pospelova M 

PROVIDER: S-EPMC12516306 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature