Transformative roles of digital twins from drug discovery to continuous manufacturing: pharmaceutical and biopharmaceutical perspectives.

ABSTRACT: Digital Twins (DTs) represent a groundbreaking development tool in the pharmaceutical and biopharmaceutical industries, providing virtual representations of physical entities, processes, or systems. This review investigates the transformative roles of DTs by examining their applications throughout the entire drug development lifecycle, from discovery to continuous manufacturing. By facilitating real-time monitoring and predictive analytics, DTs enhance operational efficiency, reduce costs, and improve product quality. Integration with advanced technologies, such as artificial intelligence and machine learning, further amplifies their capabilities, enabling sophisticated data analysis for preventive maintenance and manufacturing optimization. Despite these advantages, the implementation of

SUBMITTER: Maharjan R 

PROVIDER: S-EPMC12516570 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature