Coronary Computed Tomography Angiography Atherosclerotic Plaque Volume as A Predictor of Myocardial Blood Flow Impairment in Non-Obstructive Coronary Artery Disease.

ABSTRACT:

Background

Studies have demonstrated that patients with non-obstructive coronary artery disease (NOCAD) have an increased risk of myocardial infarction and all-cause mortality, particularly due to coronary microvascular dysfunction (CMD). Moreover, the features of atherosclerotic plaque can affect myocardial blood flow (MBF); however, data on these findings remain limited. Therefore, this study aimed to assess the impact of quantitative coronary computed tomography angiography (CCTA)-derived atherosclerotic plaque features on myocardial perfusion and MBF in NOCAD patients measured using dynamic cadmium-zinc-telluride single-photon emission computed tomography (CZT-SPECT).

Methods

Based on the CCTA results, a total of 49 NOCAD patients (stenosis <50%, 29 men, mean age 57.4 ±

SUBMITTER: Maltseva AN 

PROVIDER: S-EPMC12516756 | biostudies-literature | 2025 Sep

REPOSITORIES: biostudies-literature