Exploring the relationship between residual cholesterol, body mass index, and hypertension risk: a national cohort study.

ABSTRACT:

Background

Recent studies suggest a link between residual cholesterol (RC) and hypertension, but the mechanisms remain unclear. Exploring modifiable factors like RC may contribute to chronic disease management.

Methods

A total of 1,788 individuals aged 45 years or older were selected from the China Health and Retirement Longitudinal Study (CHARLS), which was conducted from 2011 to 2020. Participants with a baseline BMI ≥ 24 kg/m² or diagnosis of hypertension in 2013 or earlier were excluded. Here, baseline RC levels were treated as the exposure factor, BMI from the 2013 follow-up as the mediator, and incident hypertension from the 2015-2020 follow-up as the outcome variable. This study examined the effect of RC and BMI on hypertension by focusing on the role of BMI in the un

SUBMITTER: Teng TQ 

PROVIDER: S-EPMC12516858 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature