Exploring the Rheology and Clinical Potential of Calcium Hydroxylapatite-Hyaluronic Acid Hybrids.

ABSTRACT:

Background

Combining calcium hydroxylapatite-carboxymethylcellulose (CaHA-CMC) with hyaluronic acid (HA) products using Cohesive Polydensified Matrix (CPM) technology leverages the volumizing and hydrating effects of HA and draws upon the regenerative properties of CaHA-CMC, providing a potentially synergistic approach in aesthetic filling treatments. Despite this potential, the rheological and physical properties of these hybrid fillers remain unreported.

Objective

To characterize the rheological properties of CaHA-CMC blended with various CPM-HA products and identify factors influencing their physical and clinical behavior.

Methods

Hybrid fillers were prepared by mixing CaHA-CMC with different CPM-HA products at varying ratios (1:1 to 1:4 syringe CaHA:syringe CPM).

SUBMITTER: Kaczuba E 

PROVIDER: S-EPMC12516938 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature