Microencapsulated α-Tocopherol and Moringa Extract for Improved Skin Protection: Insights From Human Skin Assessment in Cosmetic Formulations.

ABSTRACT:

Background

α-Tocopherol is a potent antioxidant naturally present in human skin, protecting against oxidative damage from UV radiation and pollution. While cosmetic applications may enhance skin protection, its stability and effective delivery remain challenging. Moringa oleifera Lam. (Mo) leaves, rich in α-tocopherol and other bioactives, represent a natural alternative.

Aims

To develop and compare microcapsules containing synthetic α-tocopherol (MC α-toc) or a combination of α-tocopherol with Mo extract (MC Mo + α-toc), and to evaluate their encapsulation performance, release profile, and efficacy in cosmetic formulations.

Patients/methods

Mo extract was obtained by supercritical CO₂ extraction, yielding 232.5 ± 3.2 mg α-tocopherol·g^-1 extract. Both extra

SUBMITTER: Kessler JC 

PROVIDER: S-EPMC12516939 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature