Efficacy of Tirofiban combined with oral antiplatelet therapy in progressive ischemic stroke: A systematic review and meta-analysis.

ABSTRACT: This meta-analysis aimed to evaluate the safety and efficacy of combining tirofiban with oral antiplatelet agents in treating patients with progressive ischemic stroke. The investigators searched several databases, including PubMed, Web of Science, the Cochrane Library, CNKI, VIP, WanFang Data and Sinomed. The search was restricted to literature published before May 5, 2025, without any language restrictions. Stata software 17.0 was used to analyze the results and assess risk of bias. A total of 19 studies comprising 3,667 patients were included in the analysis. Furthermore, statistically significant differences (P<0.05) were observed when comparing the tirofiban group and the control group regarding the incidence of achieving a 3-month modified Rankin scale (mRS) score of 0-2, the Nationa

SUBMITTER: Yu Y 

PROVIDER: S-EPMC12516941 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature