Unmet needs and challenges in the diagnosis and management of antiphospholipid syndrome: a qualitative stakeholder study within the ReCONNET framework.

ABSTRACT:

Objective

Antiphospholipid syndrome (APS) is a rare autoimmune condition characterised by thrombosis and/or pregnancy morbidity in the presence of antiphospholipid antibodies. Despite the publication of updated American College of Rheumatology (ACR)/European Alliance of Associations for Rheumatology (EULAR) classification criteria in 2023, persistent diagnostic and therapeutic challenges remain. This qualitative study, conducted within the European Reference Network for Connective Tissue and Musculoskeletal Diseases, ReCONNET, aimed to map stakeholder-identified gaps in APS care across Europe to inform subsequent quantitative prioritisation.

Methods

Between February and April 2025, we conducted 16 semistructured interviews with purposively sampled stakeholders (clinicians ac

SUBMITTER: Sciascia S 

PROVIDER: S-EPMC12516966 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature