Health impacts of electronic nicotine delivery systems: an umbrella review of systematic reviews.

ABSTRACT:

Background

The rise of electronic nicotine delivery systems (ENDS) has introduced new challenges to tobacco control and regulation, particularly among young adults, raising questions about their safety. This umbrella review aimed to synthesise existing systematic reviews with or without meta-analyses to evaluate the health impacts of ENDS.

Methods

We conducted a systematic literature search via the PICO strategy across multiple databases, focusing on e-cigarettes, ENDS and e-liquids, while excluding non-nicotine e-cigarette and nicotine replacement therapies (NRTs). Health outcomes include a range of clinical diseases and physiological changes. Quality assessment was performed via assessing the methodoligcal quality of systematic reviews 2 (AMSTAR-2), and the findings were s

SUBMITTER: Kaur J 

PROVIDER: S-EPMC12516984 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature