Optimizing titanium dioxide-functionalized polymethyl methacrylate (PMMA-TiO₂) for dental applications: A systematic review on physicochemical parameters and antimicrobial outcomes.

ABSTRACT:

Introduction

Polymethyl methacrylate (PMMA) resins are widely used in dental prostheses due to their excellent physical, mechanical, and aesthetic properties. However, their susceptibility to microbial colonization can compromise oral and systemic health. Titanium dioxide (TiO₂), with its photocatalytic activity, has gained attention for its antimicrobial potential. This systematic review investigates how the physicochemical properties of TiO₂ affect its antimicrobial efficacy in PMMA-TiO₂ composites, aiming to optimize their performance and clinical effectiveness.

Methods

PubMed, Embase, Scopus, ScienceDirect, Web of Science, Google Scholar, and ProQuest were searched in October 2024. Articles were selected in two stages by two blinded researchers based on predefined eligib

SUBMITTER: Melo-Soares V 

PROVIDER: S-EPMC12517098 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature