Diagnostic accuracy of a commercial AI digital stethoscope for diagnosis of TB.

ABSTRACT:

Background

Improved TB screening requires non-invasive, low-cost, and rapid diagnostics. Digital stethoscopes utilising machine-learning approaches to analyse respiratory sounds have potential.

Methods

We assessed accuracy of a commercial digital stethoscope for TB diagnosis among TB symptomatic participants. The microbiological reference standard (MRS) was sputum TB-positive on either liquid culture, solid culture, or Xpert MTB/RIF Ultra. Adults were enrolled from South Africa, Uganda, Vietnam, and Peru, with pre-defined sampling of 60 MRS-positive and 180 MRS-negative participants over two stages. Respiratory sounds from six auscultation positions on the participant's torso were analysed. The manufacturer (blinded to MRS status) provided participant scores and a test-posit

SUBMITTER: Cox H 

PROVIDER: S-EPMC12517259 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature