Antimicrobial activity of <i>Andrographis paniculata</i> intimate wash and commercial formulations against vaginal pathogens using the broth microdilution method.

ABSTRACT:

Background

This study aims to evaluate the antimicrobial efficacy of a newly formulated Andrographis paniculata intimate wash in comparison with commercial brands (SebaMed^®, Sumber Ayu, Lactacyd^®, and Good Virtue & Co.) against vaginal pathogens. The antimicrobial activity of each formulation was tested against Streptococcus agalactiae, Escherichia coli, and Candida albicans. Additionally, Lactobacillus crispatus was tested to ensure the formulations did not inhibit normal vaginal flora.

Methods

The broth microdilution method was used to assess antimicrobial efficacy by calculating the percentage of microbial inhibition. Minimum inhibitory concentration (MIC) was determined for A. paniculata and commercial intim

SUBMITTER: Razian NRA 

PROVIDER: S-EPMC12517284 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature