Shared functional organization between pulvinar-cortical and cortico-cortical connectivity and its structural and molecular imaging correlates.

ABSTRACT: The pulvinar, the largest thalamic nucleus, is a highly interconnected structure supporting perception, visuospatial attention, and emotional processing. Such a central role relies on a precise topographical organization reflected in anatomical connectivity and neurochemical markers. Traditionally subdivided into distinct subnuclei, recent work shows that these divisions only partially explain its organization, which is better captured by continuous gradients of cortical connections along dorso-ventral and medio-lateral axes. While well studied in primates, this gradient-based architecture remains less explored in humans. The present work combines high-quality, multimodal structural and functional imaging with a whole-brain, large-scale, PET atlas mapping 19 neurotransmitter systems. By ap

SUBMITTER: Basile GA 

PROVIDER: S-EPMC12517690 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature