Postoperative gastric cancer accompanied by large-cell neuroendocrine carcinoma: A case report.

ABSTRACT:

Rationale

Large cell neuroendocrine carcinoma (LCNEC) is a type of neuroendocrine carcinoma that is a rare malignant tumor that often coexists with adenocarcinoma in the same tissue. Adenocarcinoma cells may transform into LCNEC cells. The patient was found to have a liver mass 3 years after gastric adenocarcinoma surgery. Due to the absence of neuroendocrine cells in the liver, the patient's liver lesions may undergo neuroendocrine transformation after adenocarcinoma metastasis.

Patient concerns

The patient was found to have a liver mass 3 years after gastric adenocarcinoma surgery, and the preliminary clinical diagnosis was gastric cancer with liver metastasis. The patient has no discomfort symptoms, and the relevant physical examination shows no abnormalities.

Diagnose

SUBMITTER: Chen Z 

PROVIDER: S-EPMC12517824 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature