Global burden and inequalities of bladder cancer attributable to high fasting plasma glucose: Trends 1990-2021 and Projections to 2040.

ABSTRACT: Bladder cancer (BC) is a major global health issue, with higher incidence in males and significant regional disparities. High fasting plasma glucose (HFPG), a key metabolic risk factor, is linked to BC, but its global burden and future trends remain underexplored. We calculated the number of BC deaths, disability-adjusted life years (DALYs), age-standardized mortality rates (ASMR), and age-standardized DALY rates (ASDR) related to HFPG using data from the Global Burden of Disease 2021 database. Temporal trends were assessed using estimated annual percentage change, and inequalities were analyzed using a socio-demographic index. The Bayesian age-period-cohort model projected future burden to 2040. All analyses included 95% uncertainty intervals. In 2021, HFPG accounted for 7.9% of global BC

SUBMITTER: Huang M 

PROVIDER: S-EPMC12517948 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature