Association between pretransfer cleavage-stage blastomere dynamics and pregnancy outcomes in fresh single embryo transfer cycles: a retrospective cohort study.

ABSTRACT:

Objective

To evaluate the impact of embryo blastomere cell number and dynamic changes in cell number during the morning of embryo transfer day (7:00-11:00) on clinical pregnancy outcomes in fresh single embryo transfer (SET) cycles.

Methods

A retrospective cohort study was performed, including 561 fresh SET cycles conducted between January 2022 and June 2024. Cycles were categorized into four groups based on embryo blastomere count before transfer: ≤7-cell, 8-cell, 9-10-cell, and ≥11-cell groups. We analyzed the relationship between the increase in blastomere number observed from 7:00 a.m. to 11:00 a.m. on the day of transfer and clinical pregnancy outcomes. Multivariate logistic regression analysis was utilized to assess the influence of various factors on clinical pregnanc

SUBMITTER: Wang Q 

PROVIDER: S-EPMC12518097 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature