Evaluation of non-invasive diagnostic tests for <i>Mycoplasma pneumoniae</i> pneumonia.

ABSTRACT:

Background

Accurate and timely identification of Mycoplasma pneumoniae pneumonia (MPP) remains a clinical challenge. Although nasopharyngeal swab nucleic acid testing (NAAT) and serum IgM antibody assays are widely used, their diagnostic performance varies across studies. This study aimed to retrospectively evaluate the sensitivity and specificity of the two non-invasive methods (NAAT and serum IgM antibody assays) for MPP in real-world clinical settings.

Methods

We conducted a retrospective study of adult patients hospitalized for community-acquired pneumonia (CAP) from January 2024 to October 2024. All enrolled patients underwent bronchoalveolar lavage fluid metagenomic next-generation sequencing (BALF-mNGS) and had received at least one of two non-invasive tests (N

SUBMITTER: Fan Y 

PROVIDER: S-EPMC12518258 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature