Sleep behaviors modify the association between hemoglobin concentration and respiratory infection: a prospective cohort analysis.

ABSTRACT:

Interpretation

Hb and respiratory infection showed a nonlinear U-shaped association; such a relation is modified by the chronotype sleep behavior.

Objective

To examine the association between Hb and the incidence of hospitalized respiratory infection, and to explore potential modification effects of sleep behaviors.

Methods

Included were 292,568 individuals without respiratory disease, cancer, or anemia diagnosis in the United Kingdom Biobank . Hb (g/dL) was measured at baseline. The interaction between Hb and sleep behaviors, including sleep duration, insomnia, chronotype, and daytime sleepiness with respiratory infection, was tested.

Results

The cohort was followed up at a median 12.6 years, and 16,669 incident respiratory infections (9,334 in men, 7,335 in w

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC12518324 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature