Comparative analysis of rhizosphere microbial communities and secondary metabolites in cultivated <i>Rheum officinale</i> from different regions of China.

ABSTRACT: Rheum officinale Baill., a medicinal herb rich in anthraquinones and tannins, exhibits region-specific variation in bioactive compound accumulation. Given the well-documented pharmacological properties of R. officinale Baill. including its laxative, antibacterial, anti-inflammatory and regulating intestinal function, this study integrated Illumina sequencing of rhizosphere microbiomes, HPLC quantification of 10 active components (e.g., rhein, physcion), and soil analysis across three cultivation regions Shaanxi (ZB), Hubei (HB), Chongqing (CQ). Results demonstrated significant regional disparities: ZB showed highest rhein and catechin levels, while CQ accumulated more physcion. Microbial diversity followed the order ZB>HB>CQ, with Proteobacteria and Ascomycota d

SUBMITTER: Wang Y 

PROVIDER: S-EPMC12518358 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature