A cross-sectional survey on VEXAS syndrome: insights from a global expert panel.

ABSTRACT:

Background

Vacuolization, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome is recently described, for which the diagnosis and management lack official guidelines.

Aims

To assess the diagnostic capabilities and disease management of VEXAS syndrome among physicians in the global context.

Methods

An electronic survey was sent to clinicians with expertise in VEXAS syndrome between January and February 2025 to gather real-life data on the management of VEXAS.

Results

Seventy-four clinicians completed the survey from Europe (n = 51, 68.9%), North America (n = 9, 12.2%), Australasia (n = 6, 8.1%), Asia (n = 6, 8.1%), Africa (n = 1, 1.4%), and South America (n = 1, 1.4%), mostly being hematologists (n = 24, 32.4%) and rheumatologists (n = 24, 32.4%). Maj

SUBMITTER: Ali SB 

PROVIDER: S-EPMC12518442 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature