Sleep disorders and the risk of cognitive decline or dementia: an updated systematic review and meta-analysis of longitudinal studies.

ABSTRACT:

Background

The evidence on the relationship between sleep disorders and the risk of cognitive decline or dementia remains inconsistent.

Objectives

This systematic review and meta-analysis aimed to provide updated evidence on the association between sleep disturbances and cognitive decline.

Methods

PubMed, EMBASE, and Web of Science were systematically searched from their respective inceptions to 18 February 2025. Cohort studies investigating longitudinal associations between sleep disorders and cognitive decline or dementia were included. Pooled relative risks (RRs) with 95% confidence intervals were calculated. Sensitivity analyses were conducted to evaluate the robustness of the pooled estimates. Publication bias was assessed using Egger's and Begg's tests, and meta

SUBMITTER: Zhang J 

PROVIDER: S-EPMC12518473 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature