Multimodal treatment for multifocal metastatic maxillary adenoid cystic carcinoma: A case report.

ABSTRACT: Maxillary adenoid cystic carcinoma (ACC) is rare, with pleural and brain metastases representing an unprecedented presentation. The present case report illustrates the challenges and potential for prolonged survival in such an advanced stage of malignant disease. A 52-year-old male patient presented with a left maxillary mass, initially misdiagnosed as ameloblastoma; subsequently, it was confirmed as maxillary ACC (T4aN0M0, stage IVA). Following primary tumor resection and radiotherapy, the patient developed pleural (February 2021) and brain metastases (March 2022). A multimodal treatment strategy was used, involving aggressive surgical resection of the primary tumor, comprehensive radiotherapy, systemic chemotherapy regimens and adjuvant targeted molecular therapy. By using this sequentia

SUBMITTER: He B 

PROVIDER: S-EPMC12519057 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature