Prognostic impact of cardiac dysfunctions in patients with ST-segment elevation myocardial infarction.

ABSTRACT:

Background

The incidence and impact of cardiac dysfunctions after ST-segment elevation myocardial infarction (STEMI) are not understood. We aimed to characterize the prevalence of follow-up systolic and diastolic dysfunction and their associations with long-term outcomes after STEMI.

Methods and results

This sub-study of the DANAMI-3 trial included 542 patients with STEMI. Cardiac magnetic resonance (CMR)-defined systolic/diastolic impairment was applied to define systolic/diastolic dysfunction. Systolic dysfunction was defined as left ventricular ejection fraction (LVEF) < 50 %, and diastolic dysfunction as peak filling rate/end-diastolic volume (PFR/EDV) ≤ 2.55 by CMR three months after STEMI. The primary outcome was a composite of all-cause mortality and hospitalization f

SUBMITTER: Zhou Y 

PROVIDER: S-EPMC12519244 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature