Non-invasive tests for MetALD and alcohol-related liver disease.

ABSTRACT: Metabolic- and alcohol-related liver disease (MetALD) and alcohol-related liver disease (ALD) are major drivers of the global burden of cirrhosis. While metabolic dysfunction-associated steatotic liver disease (MASLD) affects nearly one-third of the global population, ALD and MetALD, though far less common, account for a disproportionately high rate of liver-related complications and deaths. Despite this, research and clinical focus on ALD and MetALD remain limited. A critical barrier is the late stage at which these conditions are typically diagnosed, often after the onset of decompensation. In this review, we explore the potential of non-invasive tests (NITs) to change the diagnostic landscape of ALD and MetALD. NITs offer a practical and scalable means to detect liver disease at earlier

SUBMITTER: Johansen S 

PROVIDER: S-EPMC12519246 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature