Epidemiology, comorbidities, treatments and outcomes of autoimmune liver diseases: A French nationwide study.

ABSTRACT:

Background & aims

The epidemiology, clinical management, and prognosis of autoimmune liver diseases (AILDs) - including autoimmune hepatitis (AIH), primary biliary cholangitis (PBC), and primary sclerosing cholangitis (PSC) - vary according to geography and time. This study aimed to provide a comprehensive evaluation of the burden of AILDs in a Western European country.

Method

A nationwide retrospective study was performed using the French national health data system from 2009 to 2019. AIH and PBC were identified via ICD-10 codes, while PSC was defined using composite criteria. Prevalence, incidence, geographic patterns, comorbidities, treatments, liver transplant, and standardized mortality ratio were assessed.

Results

A total of 30,255 AILD cases were identified, re

SUBMITTER: Corpechot C 

PROVIDER: S-EPMC12519275 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature