Antenatal Corticosteroids and Infectious Diseases Throughout Childhood.

ABSTRACT:

Importance

International guidelines recommend the use of antenatal corticosteroids (ACS) in pregnancies at risk of imminent preterm birth before 34 weeks' gestation. However, whether ACS leads to long-term risk of infection from childhood to adulthood is unknown.

Objective

To determine whether preterm (<37 weeks' gestation) and full-term (37-41 weeks' gestation) children exposed to ACS are more susceptible to respiratory and nonrespiratory infections compared with ACS-unexposed children throughout childhood and adolescence.

Design, setting, and participants

This population-based cohort study used data from the multicenter Consortium for the Study of Pregnancy Treatments (Co-OPT) study, including data from nationwide registries for mothers and their children in Finland

SUBMITTER: Decrue F 

PROVIDER: S-EPMC12519305 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature