Higher cardiometabolic index elevates the risk of hyperuricemia in the elderly: findings from the China health and retirement longitudinal study.

ABSTRACT:

Background

Hyperuricemia (HUA) is the direct cause of gouty arthritis. The association between cardiometabolic index (CMI) and hyperuricemia remains unclear. This study aimed to examine this association in the middle-aged and elderly Chinese for preventing gouty arthritis at early stage.

Method

This study was based on China Health and Retirement Longitudinal Study (CHARLS, survey 2011 and 2015). Four logistic regression models were established. Sensitive analysis including propensity score matching (PSM) and inverse probability of treatment weighting (IPTW), etc. were applied to identify the robustness of the models. Restricted cubic spline (RCS) was adopted to further explore the non-linear relationship between the CMI and hyperuricemia. Moreover, as the HUA was caused by t

SUBMITTER: Zhong L 

PROVIDER: S-EPMC12519585 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature