Establishment of a rabbit model for microscopically assisted posterior lumbar fenestration.

ABSTRACT:

Background

Microscopically assisted posterior lumbar fenestration plays a critical role in spinal surgery, yet no animal model currently replicates this procedure.

Objective

This study aimed to rigorously simulate clinically relevant microscopically assisted posterior lumbar fenestration in New Zealand white rabbits, establishing a stable animal model for investigating postoperative recurrence and pathophysiological mechanisms, while evaluating its feasibility.

Materials and methods

Forty-eight 4-month-old male New Zealand white rabbits (weight: 2.0-2.5 kg) were randomly assigned using a number table. Preoperative assessments included general nutritional status and response to stimuli. Intravenous anesthesia was administered, followed by localization of the L5-6 inter

SUBMITTER: Jiao L 

PROVIDER: S-EPMC12519746 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature