Study protocol for a multi-site randomized clinical trial of an intervention program to promote self-management among head and neck cancer survivors with lymphedema and fibrosis [PROMISE trial].

ABSTRACT:

Background

Lymphedema and fibrosis (LEF) secondary to head and neck cancer (HNC) treatment is a chronic process and a lifelong commitment to self-care. Although prospective data is lacking, a program of self-management may reduce LEF progression and minimize associated functional impairments and symptom burden. Barriers to long-term LEF self-care include lack of standardized self-care protocols as well as lack of LEF-related knowledge, skills, self-efficacy and adherence among HNC survivors. The objective of this study is to evaluate the effectiveness of a standardized lymphedema and fibrosis self-management program (LEF-SMP) in reducing LEF-associated symptom burden and functional deficits, thereby improving quality of life (QOL).

Methods

We will conduct a 3-year, multi-sit

SUBMITTER: Deng J 

PROVIDER: S-EPMC12519825 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature