Stress response regulation to extracellular polymeric substances biosynthesis in Bacillus licheniformis.

ABSTRACT:

Background

The diverse metabolic mechanisms underlying bacterial extracellular polymeric substances give rise to a wide array of components with distinct functionalities, including exopolysaccharides (EPS) and poly-γ-glutamic acid (γ-PGA). The coordinated synthesis of various types of extracellular polymeric substances necessitates comprehensive investigation from a global regulatory perspective.

Results

In this study, we examined the impact of multiple environmental stressors on Bacillus species, revealing that the EPS and γ-PGA produced respond to stress through metabolic and cellular process reorganization. The overexpression of global transcriptional regulators influenced the production of EPS and γ-PGA differently. Specifically, quorum sensing-related global regulators

SUBMITTER: Wei X 

PROVIDER: S-EPMC12519863 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature