Burden of Seasonal Human Coronavirus Infections in Hematopoietic Cell Transplant Recipients.

ABSTRACT:

Background

Community respiratory viruses, such as seasonal human coronavirus (HCoV), commonly infect hematopoietic cell transplant (HCT) recipients. Recognizing the risk factors and outcomes of HCoV infections in HCT recipients is essential for the future development of potentially lifesaving therapeutics.

Methods

We performed a retrospective review of all HCoV-infected HCT recipients from September 1, 2015 to August 31, 2017, at our institution. Patients were classified with upper respiratory tract infection (URI) or lower respiratory infection (LRI) based on predefined definitions for respiratory viral infections in HCT recipients. Patient data were collected to identify risk factors for HCoV LRI, and to calculate an immunodeficiency scoring index (ISI). Univariate and mul

SUBMITTER: Khawaja F 

PROVIDER: S-EPMC12519910 | biostudies-literature | 2025 Sep-Oct

REPOSITORIES: biostudies-literature