Younger Age and Viral Triggers Were Associated With Post-Infectious Bronchiolitis Obliterans in French Children.

ABSTRACT:

Aim

Post-infectious bronchiolitis obliterans (PIBO) is a rare but severe chronic paediatric obstructive lung disease, characterised by the obliteration of small airways following severe lower respiratory tract infections. Epidemiological data in Europe remain limited.

Methods

This multicentre retrospective study examined the characteristics of paediatric patients diagnosed with PIBO from 2017 to 2023. Carried out by the French Reference Centre of Rare Lung Diseases network, it was based on clinical and radiological criteria and included age at diagnosis, medical history, symptoms, initial triggers, treatment, and outcomes.

Results

The study comprised 147 patients (58.5% male) diagnosed by 18 tertiary centres at a median age of 22 months. Most (83.7%) were hospitalised

SUBMITTER: Mazenq J 

PROVIDER: S-EPMC12520280 | biostudies-literature | 2025 Nov

REPOSITORIES: biostudies-literature