High unawareness of kidney dysfunction in European older adults and the importance of early detection through comorbidities.

ABSTRACT:

Introduction

Chronic kidney disease (CKD) continues to go undiagnosed at significant rates in Europe, with few exploring the underlying mechanisms which prompt detection. Considering the causal link of numerous health conditions and CKD, this study investigates how individual and combined comorbidities are associated with the likelihood of CKD detection.

Materials and methods

In a large population study (n = 22,386) of older adults (50+) among 11 European countries and Israel, we calculate the prevalence of undiagnosed CKD using serum-equivalent cystatin C values, derived from dried blood spots. Logistic regressions are estimated to predict factors related to CKD diagnosis among the population and among those with diagnosed vs. undiagnosed CKD.

Results

Unawareness of

SUBMITTER: Horton HM 

PROVIDER: S-EPMC12520349 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature