Conductive Nanocomposite Hydrogels for Neural Tissue Engineering: A Systematic Scoping Review of Recent Trends.

ABSTRACT: Conductive nanocomposite hydrogels (CNHs) represent a promising tool in neural tissue engineering, offering tailored electroactive microenvironments to address the complex challenges of neural repair. This systematic scoping review, conducted in accordance with PRISMA-ScR guidelines, synthesizes recent advancements in CNH design, functionality, and therapeutic efficacy for central and peripheral nervous system (CNS and PNS) applications. The analysis of 125 studies reveals a growing emphasis on multifunctional materials, with carbon-based nanomaterials (CNTs, graphene derivatives; 36.8%), metals (Iron oxides, gold, etc.; 24.0%), conductive polymers (PEDOT, PPy, etc.; 16.0%), and hybrid systems dominating due to their synergistic electrical, mechanical, and bioactive properties. For CNS rep

SUBMITTER: Moghaddasi M 

PROVIDER: S-EPMC12520499 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature