SuFEx-Enabled Catalytic Synthesis of Fluorescent Organosulfur Polymers for the Rapid Detection of Explosives.

ABSTRACT: The rapid and straightforward detection of explosive molecules is crucial for ensuring public safety and national security. Herein, a new series of conjugated polymers, referred to as the SP series, incorporating pentiptycene structures with organosulfur (sulfide and sulfonate ester) side chains, which is developed via sulfur(VI)-fluoride exchange (SuFEx) click chemistry. These polymers enhance the detection capabilities of nitroaromatic explosives through improved fluorescence quenching mechanisms. The method involved synthesizing β-sulfido sulfonyl fluorides via superbase-catalyzed thia-Michael reactions, introducing sulfonates through SuFEx conjugation, and assembling the polymers via palladium-catalyzed Sonogashira coupling. The SP-7 polymer, in particular, shows exceptional performanc

SUBMITTER: Lee SB 

PROVIDER: S-EPMC12520564 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature