Current treatment of lupus nephritis: an overview of the new guidelines.

ABSTRACT:

Introduction

Given the relevance of renal involvement in systemic lupus erythematosus (SLE) and new approaches to the disease and its treatment, this article aimed to synthesize the main updates in the diagnosis, management, and treatment of lupus nephritis (LN), based on recent publications of international reference guidelines in nephrology and rheumatology, in addition to highlighting aspects of interest from the 2024 national guidelines of the Brazilian Society of Rheumatology (SBR). The treatments for each class of lupus nephritis are described, as well as the therapeutic targets, underlining similarities and differences between the guidelines. In general, they recommend that induction ("initial") treatment of proliferative classes be performed with monotherapy using mycopheno

SUBMITTER: Sales GTM 

PROVIDER: S-EPMC12520630 | biostudies-literature | 2025 Oct-Dec

REPOSITORIES: biostudies-literature