Examining associations between human milk fatty acids, oligosaccharides, and early infant cognitive, language and motor development in the CHILD cohort study.

ABSTRACT:

Introduction

Human milk fatty acids and human milk oligosaccharides (HMOs) are milk components inconsistently associated with neurodevelopment. The objective of this research is to examine the link between fatty acids, HMOs and neurodevelopment.

Methods

This study includes a subset of 240 parent-infant pairs from the Edmonton site of the CHILD Cohort Study. At 3-4 months post-partum, breastfeeding parents provided a milk sample which was analyzed to identify 20 fatty acids and 19 HMOs. Research assistants administered the Bayley Scales of Infant and Toddler Development at 1 and 2 years of age, comprising cognitive, language and motor development scales (standardized to a mean of 100 and a standard deviation of 15; higher scores indicate better development). Adjusted linear r

SUBMITTER: Turner SE 

PROVIDER: S-EPMC12520911 | biostudies-literature | 2025

REPOSITORIES: biostudies-literature