Optimization of ALPPS stage II timing with the APRI/ALBI score-an international, multicenter cohort study.

ABSTRACT:

Background

Primarily unresectable liver tumors may be approached by the Associating Liver Partition and Portal vein Ligation for Staged Hepatectomy (ALPPS) procedure. Post-hepatectomy liver failure (PHLF) poses the most significant risk factor for poor outcomes. The AST-to-platelets ratio index (APRI)/albumin-to-bilirubin index (ALBI) score has been proposed as an easy and routinely available score to monitor liver function. Here, we explored the predictive capability of the APRI/ALBI score to determine PHLF and perioperative morbidity to help determine the optimal timing of the 2nd stage of ALPPS.

Methods

Based on the international multicenter ALPPS registry, patients from 2012 to 2020 with an available APRI/ALBI score were included. Postoperative outcomes (clinically relev

SUBMITTER: Jonas JP 

PROVIDER: S-EPMC12521025 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature