Sarcopenia and gender disparities in liver transplant waiting lists: evaluating predictive scores and delisting risks.

ABSTRACT:

Background

The model for end-stage liver disease (MELD) and model for end-stage liver disease-sodium (MELD-Na) scores are the most widely used for prioritizing patients on the liver transplant (LT) waiting list. However, the quality and accuracy of these scores are questionable. Among the most significant limitations we found the disparity in access to transplantation by gender, with excess mortality demonstrated among women on the waiting list. There is also a lack of consideration for sarcopenic status, which negatively impacts those patients. The gender equity model for liver allocation (GEMA) score has recently been shown to be more discriminating, reducing mortality in women. However, this score still does not consider sarcopenic status. The main objectives of this study were

SUBMITTER: Wasielewski E 

PROVIDER: S-EPMC12521030 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature