The Impact of Melatonin Supplementation on Various Aspects of Polycystic Ovary Syndrome: A Systematic Review and Meta-Analysis.

ABSTRACT:

Background and aims

Polycystic ovary syndrome (PCOS) is a prevalent gynecological condition affecting women of reproductive age, with implications for multiple aspects of women's health. Recent research indicates that melatonin (MLT) may enhance several dimensions of this syndrome via various mechanisms. Consequently, this study was undertaken to systematically evaluate the impact of MLT supplementation on different aspects of PCOS.

Methods

According to the PRISMA guideline, we identified studies published between January 2013 and November 4, 2024, through a comprehensive electronic search of several reputable databases, including Web of Science (WoS), PubMed (MEDLINE), ProQuest, Scopus, and Google Scholar, utilizing MESH keywords. A meta-analysis was conducted employing a r

SUBMITTER: Shoarishoar SS 

PROVIDER: S-EPMC12521052 | biostudies-literature | 2025 Oct

REPOSITORIES: biostudies-literature